How does a cortisone shock therapy (pulse therapy) actually work?

The procedure usually begins one day before the actual treatment with a blood and urine examination. In particular, the blood cells, the erythrocyte sediment rate and the urine are examined for signs of infection. Since Cortisone weakens the immune system, it is very important to exclude possible infections beforehand.

In addition, medication for stomach protection and Heparin for thrombosis prophylaxis are often obtained before the start of treatment. These protective measures will continue for a few days beyond the treatment cycle.

Then cortisone for three to five days

Followed by three to five days with high-dose cortisone infusions. The infusions are usually administered in the morning. An infusion consists e.g. from 1000 mg of methylprednisolone (Urbason®). But it can also be selected other active ingredients, the dose varies depending on the potency.

The most common side effects of cortisone shock therapy are nausea and headache. The best way to avoid this is to lie down after the infusions and drink plenty of water.

All in all, the cortisone shock therapy is therefore no pleasure. But if it actually reduces the thrust or the pains, it may be worth it. But there are divided views among those affected. In the official therapy guidelines, however, it is admitted.

Read also:
What side effects can occur under the corticosterone (glucocorticoid) push therapy?

Author: Dr. med. Julia Hofmann

Do you have your own experiences or a different opinion? Then write a comment (please observe rules).
Comments (11)
Side Effect Urbason 1g Infusion
11 Wednesday, 19 April 2017 at 14:36
Although I do not have MS, I have received Urbason infusions once a day for 3 consecutive days as therapy for a mass disc prolapse. An improvement of my complaints did not bring this.
After some time, the HA did a blood count and found that there was a significant increase in leucocytes (previously my blood count was o.B.).
Now I have read this as a possible side effect with this drug. Has anyone had similar experiences?
Cortisone-shock therapy
10 Sunday, April 16, 2017 at 08:13
Admission to the clinic due to gait disorder. In the CSF examination increased protein and a few cells were detected. At V.a. CIPD 1000 mg prednisolone were infused on 5 days under gastric and thrombosis protection. - At home no particular after-effects but improvement of the gait disturbance can be felt only after 10 days. With omission of sugar, further taking of blood pressure medication as always no special occurrences. Am reappointed and re-shock therapy 5 weeks after KH discharge re-ordered.
Side effects pulse therapy
9 Monday, 27 February 2017 08:34
I received a cortisone pulse therapy, 5 days ago, about three years ago. Not in an acute episode, but because I can not do basic therapy for other reasons. In advance: My sensations, Lhermitte signs, have improved about 3 months after pulse therapy.
The side effects were, however, "crisp". So the blood pressure completely derailed, in the evening over 200/90, in the morning still 190/80. In addition, my leukos have increased to 36,000, my intraocular pressure to 37. My blood sugar value, I have not even measured.
The therapy was life threatening for me and I was close to blindness if I had not received an ophthalmologist appointment at short notice.
I will not get involved in cortisone pulse therapy that fast.
Cortisone push therapy
8 Friday, January 20, 2017 at 21:03
For four years, infusion with cortisone has been a blessing to me. It lasts about 10 months. I have MS and endure it much better. Thanks to the medicine
My cortisone therapy and something else
7 Thursday, January 19, 2017 at 21:24
In my optic neuritis (visual difficulties), I received cortisone intravenously for more than one week. Total 6500 mg. First 5 days 1000 mg (1g), then fast down 500 mg and then 250 mg for 2 days.
After that an injection (ATC / ACT or what called the doctor and no smaller doses).
Since I have been suffering from MS for 20 years, I have often received cortisone therapy.
My advice: Since taking Sphingolin I have had no relapses (in the last 2 years). No idea if this is coincidence or effect of nutritional supplement sphingolin.
Cortisone shock therapy
6 Thursday, January 28, 2016 at 11:34
Hello everybody,
Although I have no MS, but also a chronic disease.
Had 3 * 500 mg cortisone last week.
I am fine. no sleep disorders. On the contrary, after the i.V could stroll for hours in the city and eat. Then managed the 240 stairs to the top floor of the hospital. Went back to the office after being released.
To Lilo
5 Wednesday, January 13, 2016 at 19:21
Hello Lilo,

Yes that's true. The risk of cataracts increases with prolonged cortisone therapy, both for tablets and prolonged topical administration of cortisone-containing eye drops.
However, this is just a risk increase, so it does not have to happen. Cataract is just one of many possible long-term side effects of cortisone. The question is always whether the benefit of a suppressed MS boost is not greater than the benefit of the least possible risk of side effects. This can only be answered individually, even a doctor is there a maximum of a guide.

All the best and kind regards
Dr. J. Zorn (from the navigator team)
Pulse therapy cortisone
4 Wednesday, January 13, 2016 at 18:15
Cortisone speeds the cataract
Is that correct?
3 Monday, 06 April 2015 at 19:25
Cortisone is not a therapy to prevent relapses in MS. It is used in acute cases. Please do not think that cortisone can prevent relapses. That would be totally wrong.
Cortisone push therapy
2 Saturday, January 17, 2015 at 16:31
Six years ago MS was diagnosed (then 49). 2 times a year I get cortisone by infusion (500) for 3 days and can say that I did not have to experience a boost in this long time.
Well, I'm convinced.
Cortisone pulse therapy
1 Monday, January 05, 2015 at 07:07
I am in Vivantes Neukölln every 3 months for 3 days and get 3x cortisone - 10 times this time - result: I can walk reasonably well and I did not fall anymore !!!